When designing pipelines for transporting CO2 in dense-phase, the complex decom-pression behavior places high demands on the material toughness. However, due to the small number of full-scale burst test results in CO2 available to date that addition-ally encompass only a narrow envelope of geometries and material properties, it is difficult to derive both validated and practicable requirements for pipeline design. At the same time, the established toughness concepts based on Charpy V-notch (CVN) impact energy become questionable for modern line pipe steels, since the CVN impact test loses significance for high-strength steels exhibiting high CVN toughness levels. With the intention of expanding the database for the subsequent derivation of optimized design rules, a numerical modeling approach was applied in this study. Multiple pipe diameters and wall thickness/diameter ratios were evaluated to understand the influence of toughness and steel grade on arrest performance of pipes carrying dense-phase CO2.